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Pro Hormones – What You Need To Know In 2025 (Updated)

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Prohormones have been a staple in the fitness and bodybuilding community since 1996. Over the years, these compounds have undergone significant transformations, especially in light of the regulatory landscape introduced in 2004. The laws implemented then were designed to ensure prohormones’ safety, efficacy, and legality. This marked a turning point, leading to a new generation of prohormones that aim to deliver results with fewer associated risks and side effects.

While the current generation of prohormones is not entirely free from potential drawbacks, the risks have been substantially reduced. It remains crucial for users to be well-informed about the specific prohormones they choose, ensuring they align with their fitness goals and are cycled correctly. Our comprehensive guide covers essential aspects of prohormone use to aid in this journey, from common compounds to stacking strategies, potential side effects, and the critical role of post-cycle therapy (PCT).

If you don’t see a pro hormone you want us to go over, leave a comment below or send us an email.

 

pro hormones old vs new

What Are Pro Hormones?

Pro hormones are compounds that are precursors to hormones and can be converted into active hormones in the body. Bodybuilders and athletes often use them to increase muscle mass, strength, and performance. When you take a pro hormone, it converts to anabolic hormones in the body. The resulting effects are seen through several pathways. But, generally, the most important effects are on the body’s Androgenic, Estrogenic, and Progestogenic receptors. Like anabolic steroids, pro hormones are androgen receptor agonists. A strong androgen receptor agonist will present effects related to increased testosterone.†

Some effects can include increased:

  • Aggression†
  • Sex drive†
  • Muscle strength†
  • Muscle mass†
  • Muscles feel denser and more solid †

As well as an increased risk of side effects related to high androgen levels.

These can include but are not limited to increased susceptibility to hair loss and acne.†

Pro hormones also affect your estrogenic and progestogenic receptors, which react similarly. Pro hormones that convert to estrogen and progesterone can support increased mass and strength.†

However, the catch is that considerable mass gains are often lost after the cycle is over. This is likely due to water retention more than anything else. This conversion also comes with its own set of risks and sides. Estrogenic side effects can include, but are not limited to:

  • Increased water weight†
  • Increased susceptibility to fat gain†
  • And gynecomastia (swelling of the breast tissue in men)†

Pro hormones are often categorized as being androgenic, estrogenic, or both. This is typically based on their primary method of action. All pro hormones will have some degree of androgenic effect. But, each pro hormone can differ in its impact on other body systems.†

Typically, strong androgens are useful for promoting strength gains. This is via the central nervous system (CNS) stimulation. Therefore, a strong androgen is often similar to Dihydrotestosterone (DHT). Furthermore, some will promote enhanced red blood cell production, which is why users usually experience larger pumps and vascularity.†

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What’s Changed?

As we mentioned before, the pro hormones available today differ from those available before the US Congress passed the Anabolic Steroid Control Act of 2004. The new generation of pro hormones has a better delivery system and absorption rate. This means it’s not as taxing on your liver.†

Liposomal Delivery System:

Liposomal technology has been used in the medical field as a carrier for drugs. But only now has it made its way into nutrition supplements. Liposomes have a hydrophobic core with a hydrophilic shell. This simultaneously protects the molecule from degradation while allowing it to be more soluble.†

Cyclosome™ Delivery:

Cyclosome™ Technology is another liposomal delivery technology. This approach can help increase pro hormone solubility and vesicle stability. This delivery method controls the in vivo fate of hydrophobic compounds and avoids the burst release of pro hormones from the vesicle. This allows the ‘Trojan Horse’ to deliver pro hormones and testosterone boosters to the systemic circulation by the intestinal lymphatic route. Almost all previous Oral capsules and tablets manufactured to increase testosterone are involved in the “first pass effect.” This renders the active compounds virtually useless.†

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Common Compounds:

There are a bunch of different compounds and different ways to stack them.

This guide will cover the following:

  • Well-known compounds and their other names
  • Possible Effects
  • Side effects
  • Stack-ability
  • Cycle lengths and types

*As with every product, results vary from person to person. Results are not guaranteed.*


1-Androsterone:

1-Andro To 1-Test

 

Other Names:
  • 1-Androsterone / 1-Andro
  • 1-DHEA / 1DHEA
  • 1-Dehydroepiandrosterone
  • 1-androstene-3b-ol-17-one
  • 3b-hydroxy-5a-androst-1-en-17-one
  • 3b-hydroxy-androst-1-ene-17-one
  • 3-hydroxy-5-androst-1-en-17-one
Popular Standalone Products:
Featured Blend Products:
Run Down:
  • Converts To 1-Testosterone†
  • Dry, Lean Muscle Mass Gains†
  • Increased Strength†
  • No Bloating/Estrogen Activity†
  • Good For Stacking†
  • Good For Cutting†
  • Increase Vascularity†

What Is 1-Andro?

1-Andro, also known as 1-DHEA, is a legal prohormone that undergoes a series of conversions within the body, eventually metabolizing into the active steroid 1-Testosterone. This conversion process involves the metabolization of 1-Andro into 1-testosterone (dihydroboldenone) and 1-androstenedione, both of which are positional isomers of testosterone and androstenedione. The subsequent conversion to dihydroboldenone is where the primary muscle-building benefits originate.†

What To Expect From 1-Andro:

1-Andro has been substantiated by research and is popular for its various benefits. Generally, it is effective in increasing lean muscle mass, enhancing strength, and boosting aggression, making it a sought-after supplement for both bulking and cutting phases.†

  • For bulking, products with higher concentrations of 1-Andro, such as 1-Testosterone, are recommended, potentially yielding faster results.†
  • Conversely, formulas like 1-AD may be better for cutting due to their slower breakdown. The label states it has 75mg of 1-Andro; it actually has 75mg of 1-Andro Decanoate, which yields 47 mg of 1-Andro. This is because of an additional ester chain, which helps regulate hormonal fluctuations.†

Additionally, it’s noteworthy that these products may contain supplementary ingredients. For instance, 1-Testosterone includes grapefruit extract, which slows the breakdown of 1-Andro, while 1-AD incorporates laxogenin, providing joint support and anabolic effects without hormonal effects. So if you’re unsure if you want to hop into the pro hormone game, laxogenin is another great option. Because it is a plant steroid, laxogenin isn’t hormonal. Women can also supplement it to improve strength, recovery, and joint pain. However, in this formula, you may only notice joint support from laxogenin.†

On the other hand, Chosen 1 from Blackstone Labs is a blend. This blend contains both esters and unesterified 1-Andro/1-DHEA. So it’s like getting the benefits of both 1-Testosterone and 1-AD, but at a much lower dose.†

Differences Between Hi-Tech 1-AD and 1-Testosterone:

  • Hi-Tech 1-AD: Converts to 1-Testosterone and is a milder hormone, providing cleaner gains and significant strength increases. It suits those seeking a balanced muscle gain and strength approach.†
  • Hi-Tech 1-Testosterone: 1-Testosterone, with its unique 1,2-double bond structure in the A ring (as opposed to the 4,5-double bond in standard testosterone), is metabolized differently. This slight modification means it cannot be converted to estrogen via aromatase nor into DHT, making it a stable molecule resistant to most traditional metabolism routes. It is often referred to as a “dry” compound, suitable for both cutting and bulking phases due to its strength benefits.†

1-Andro Side Effects:

As with any prohormone, users should be mindful of potential side effects. These may include acne, hair loss, prostate growth, cardiovascular issues, increased liver and kidney values, and testicular atrophy. Additionally, some individuals may experience low libido and lethargy, although these effects typically subside during post-cycle therapy (PCT).†

Because 1-Andro only affects androgenic receptors, the estrogenic side effects aren’t expected. Remember that side effects like acne and hair loss have a higher potential if you are already susceptible to them.†

Treating Side Effects:

We recommend taking an on-cycle support supplement like Gear Support. Products like this are going to help cut the potential for side effects. You would take it with your chosen pro hormones and stop during your PCT. You can try products like D-Aspartic Acid, Maca, Horny Goat Weed, or blends like Score! XXL for low libido.†

We encourage you to take a multivitamin with B Vitamins for your skin and hair care. You can also consider Fish Oil, Omega 3, or NAC, which benefit your whole body, hair, and skin. For acne prevention, you can try a ton of OTC cleansers; look for ones with salicylic acid and/or benzoyl peroxide.†

How To Cycle 1-Andro:

1-Andro is typically cycled for up to 8 weeks, followed by a 4-week PCT phase. Since each bottle generally covers a 4-week cycle, a second bottle is needed for an 8-week cycle.†


4-Androsterone:

4-Andro To Test

Other Names:
  • 4-Androsterone / 4-Andro
  • 4-DHEA / 4DHEA
  • 4-Dehydroepiandrosterone
  • 4-androstene-3b-ol-17-one
  • 3b-Hydroxy-4-androsten-17-one
  • 3β-hydroxyandrost-4-en-17-one
  • 3β-hydroxy-D4-androsten-17-one
Popular Standalone Products:
Featured Blend Products:
Run Down:
  • Converts To Testosterone†
  • Mass Gains†
  • Strength Gains†
  • Increased Sex Drive & Libido†
  • More Energy†
  • Helps Accelerate Muscle Recovery†
  • Supports Better Overall Mood†
  • Helps Reduce Muscle Fatigue†
  • Increases Protein Synthesis†

What Is 4-Andro?

4-Andro, also known as 4-DHEA, follows a similar conversion process to 1-Andro, undergoing a two-step transformation to become the target hormone. In the case of 4-Andro, this conversion leads to the production of testosterone. Initially, 4-DHEA converts to 4-androstenediol (4-adiol) before ultimately being metabolized into testosterone.†

What To Expect From 4-Andro:

Considered a ‘wet gainer,’ 4-Andro is associated with testosterone conversion, which may result in estrogen conversion and subsequent water retention. Consequently, users may experience substantial gains in muscle mass and strength. Due to the potential for water retention, 4-Andro is primarily recommended for bulking cycles, although it can be included in stacks for diverse objectives.†

Different products and dosages may yield varying effects. For instance, Blackstone’s Brutal 4ce blends 4-Andro, Hi-Tech’s Androdiol incorporates laxogenin, and LG’s 4 Andro comprises solely 4-Andro.†

What sets 4-Andro apart is its direct conversion to testosterone, bypassing intermediary precursors. This leads to accelerated gains, faster recovery, and a reduction in certain side effects associated with other prohormones like 1-Andro. Cycling with 4-Andro often enhances libido without inducing lethargy, offering users a heightened sense of vitality and well-being.†

Andro Side Effects:

Given the potential for estrogen conversion, users face the risk of related side effects, including water retention, fat gain, and gynecomastia. Additionally, common prohormone side effects such as acne, hair loss, cardiovascular issues, and aggression may occur. However, unlike methylated prohormones, 4-Andro is non-toxic to the liver.†

Treating Side Effects:

To mitigate estrogen-related risks, users may consider incorporating aromatase inhibitors (estrogen blockers) into their cycle or post-cycle therapy (PCT). These inhibitors help regulate estrogen conversion, minimizing the likelihood of adverse effects.†

For the other side effects, you can follow the same protocol as 1-Andro. NAC, Fish Oil, Multivitamins, and OTC acne cleansers. Because the 4-Andro is not methylated, you do not need to take on cycle support. However, you can take NAC or Milk Thistle if you are still concerned.†

How To Cycle 4-Andro:

Typically, 4-Andro is cycled for up to 8 weeks, followed by a 4-week PCT phase. Beginners may opt for shorter cycles (4 to 6 weeks) to assess their tolerance and response to the prohormone.†


19-Nor-4-Androstenediol:

19-NOR To Nan

 

 

Other Names:
  • 19-Nor-DHEA
  • 19-Nor-Andro
  • 19 NorAndrosterone
  • 19 Nor Dehydroepiandrosterone
  • NorAndrost-4-ene-3b-ol, 17-one
  • 19-Norandrost-4-ene-17-one
Popular Standalone Products:
Featured Blend Products:
Run Down:
  • Converts To Nandrolone†
  • Good For Stacking†
  • Increase Strength†
  • Dry, Lean Muscle Mass†
  • Supports Joint Health†
  • Boost Endurance†
  • Does Not Aromatize to Estrogen†
  • Does Not Convert to DHT†

What Is 19-Nor-DHEA?

19-Nor-4-Androstenediol, often referred to as 19-Nor-DHEA, operates differently than other discussed compounds, functioning more as a pre-prohormone. Through a two-step conversion process, 19-Nor-DHEA ultimately transforms into Nandrolone (Deca), a well-known anabolic compound.†

What To Expect From 19-Nor-DHEA:

Although extensive research is lacking, users have reported experiencing strength gains and the accrual of lean muscle mass with 19-Nor-DHEA. Results, however, may vary among individuals. This prohormone is particularly recommended for users susceptible to side effects, as Nandrolone generally exhibits milder effects compared to testosterone. Consequently, seasoned prohormone users may find its effects comparatively less pronounced.†

19-Nor-DHEA is generally favored by those seeking to enhance muscle growth, strength, and fat loss simultaneously. It is often regarded as suitable for individuals prioritizing strength gains, although it can also complement cutting stacks for physique-oriented goals.†

Notably, Blackstone Labs’ Abnormal features a blend formulation, while Hi-Tech’s Deca-Durabolin solely contains 19-Nor-DHEA.†

19-Nor-DHEA Side Effects:

With Nandrolone’s relatively mild nature, the risk of side effects is reduced compared to testosterone-based compounds. However, water retention and decreased libido have been reported among users, with 19-Nor-DHEA demonstrating a higher propensity for water retention than 4-Andro.†

Treating Side Effects:

To mitigate potential side effects, users may consider incorporating an estrogen blocker during their cycle. For libido support, supplements like D-Aspartic Acid, Maca, Horny Goat Weed, or blends such as Stamina Rx can be beneficial.†

Additionally, post-cycle therapy (PCT) is essential to restore natural testosterone levels. While on-cycle support is not mandatory, supplements like NAC or Milk Thistle may be taken for added liver support.†

How To Cycle 19-Nor-DHEA:

A typical cycle for 19-Nor-DHEA lasts up to 6 weeks, given its propensity to suppress natural testosterone production. Following the cycle, a 4-week PCT phase is essential for hormonal recovery. Beginners are advised to opt for shorter cycles to gauge their response to the prohormone and minimize potential risks.†


1,4-Androstadienedione:

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Other Names:
  • 1,4 AD
  • 1,4-Andro
  • 1, 4-androstadiene-3, 17-Dione
  • 1,4-Androstadienedione
Popular Standalone Products:
  • Equibolin, By Hi-Tech Pharmaceuticals ~ 75mg
Featured Blend Products:
Run Down:
  • Converts To Boldenone†
  • Dry, Lean Muscle Mass†
  • Improve Recovery Time†
  • Increases Strength†
  • Increases Appetite†
  • Boosts Energy†

What Is 1,4-Andro?

1,4-Androstadienedione, commonly called 1,4-AD, undergoes a two-step conversion process to reach its target hormone, boldenone. Boldenone, akin to testosterone but with an additional double bond, exhibits reduced affinity for enzymes responsible for estrogen conversion. This characteristic distinguishes it as a potent compound for lean muscle mass gains with minimal water retention.†

What To Expect From 1,4-Andro:

Notable for its ability to significantly increase hunger, Equipoise, containing 1,4-AD, is primarily recommended for bulking cycles. Alongside increasing appetite, users can anticipate gains in muscle mass and strength attributed to boldenone’s anabolic properties.†

Despite a low conversion rate to estrogen, 1,4-AD ensures relatively bloat-free cycles while still deriving benefits associated with estrogenic conversion. However, the effects of 1,4-Andro may manifest more gradually (typically 2-3 weeks) compared to other compounds.†

1,4-Andro Side Effects:

Due to its highly anabolic nature, the risk of side effects with 1,4-Andro is relatively low. However, Equibolin is recommended for more experienced users due to its potency.†

Treating Side Effects:

Supplementation with an estrogen blocker can aid in averting potential side effects associated with estrogen conversion. Additionally, on-cycle support supplements like NAC or Milk Thistle can be considered for individuals seeking an extra layer of protection.†

How To Cycle 1,4-Andro:

Results from 1,4-Andro supplementation typically become noticeable within 3-4 weeks, with cycles lasting up to 8 weeks followed by a 4-week PCT phase.†


Epiandrosterone:

EpiAndro to dht

Other Names:
  • 3-hydroxy-androstane-17-one
  • trans-Androsterone
  • Isoandrosterone
  • 3-Epiandrosterone
  • Epi-Andro
  • 3B-Hydroxy-5a-androstan-17-one
  • 5a-Androstan-3a-ol-17-one
  • 3Beta-hydroxy-5alpha-androstan-17-one azine
Popular Standalone Products:
Featured Blend Products:
Run Down:
  • Converts To DHT†
  • “Hardening Agent”†
  • Fat Loss†
  • Improve Recovery Time†
  • Increase Strength†
  • Support Libido†
  • Increase Vascularity†

What Is Epi-Andro?

Epiandrosterone was first identified in the 1930s. It is a metabolite of DHEA (Dehydroepiandrosterone).†

Although not the strongest androgen, it is a popular cutting prohormone. Users take it to support dry, lean muscle gains, improve vascularity, and boost libido.†

What To Expect From Epi-Andro:

Epiandrosterone is effective for achieving lean, dry muscle while increasing vascularity and libido.†

It is milder than other prohormones but may have mild stimulant effects, making it suitable as a pre-workout.†

Notably, Epi Andro 50 by LG Sciences contains Epicatechin, a compound found in green tea and dark chocolate. Epicatechin can inhibit myostatin, which may promote muscle growth.†

Epi-Andro Side Effects:

Epiandrosterone does not convert to estrogen, so estrogen-related side effects are unlikely.†

However, some of it may convert to DHT (Dihydrotestosterone). This can lead to hair-related issues, especially in those prone to hair loss.†

Some users may also experience joint discomfort during use.†

Treating Side Effects:

On-cycle support is not required, but it can help:

  • Liver support: NAC or Milk Thistle
  • Joint support: Joint-RX or similar supplements
  • Hair support: Minoxidil for hair-loss concerns†

These measures can help minimize potential side effects.†

How To Cycle Epi-Andro:

  • Cycle length: Up to six weeks†
  • Follow-up: After the cycle, a 4-week PCT is recommended to support hormone balance and reduce risks†

Effects may take time to appear, so some users extend cycles slightly for optimal results†


HydroxyProgestins:

HydroxyProgestins

Other Names:
  • 5aOHP: 17beta {3ketoethyl}-androstane-3-one, 17a-ol 
  • 1,4-OHP: 17beta {3ketoethyl}-androsta-1,4-diene-3-one, 17a-ol
Popular Standalone Products:
Featured Blend Products:
Run Down:
  • Converts To DHT†
  • Dry, Lean Muscle Gains†
  • Strength Gains†
  • Increase Appetite †
  • Helps Accelerate Muscle Recovery†

What Are HydroxyProgestins?

HydroxyProgestins are a new class of prohormones. They are similar to 1-Testosterone or Boldenone and support muscle growth.†

What To Expect From HydroxyProgestins:

HydroxyProgestins work differently from DHEA prohormones. They use the enzyme 17,20 Lyase to become active. This process removes a side chain at the 17-position, producing an active steroid.†

(chemical name: 17beta-{1-Ketoethyl}-androstane-3-one, 17a-ol)

This anabolic progestin converts to stanolone (DHT). It may act as a myostatin inhibitor, raise androgen levels, and increase messenger RNA activity. 5aOHP offers benefits similar to Winstrol, helping create a lean physique without the hair loss often seen with Winstrol.†

(chemical name: 17beta-{1-Ketoethyl}-androsta-1, 4-diene-3-one, 17a-ol)

This prohormone converts to Boldenone, promoting appetite, recovery, and lean mass gains. It supports muscle growth without causing significant water retention.†

HydroxyProgestin Side Effects:

Hydroxyprogestins do not convert to estrogen or progesterone, reducing related side effects. However, supporting liver health during and after the cycle is recommended.†

Treating Side Effects:

To support liver function, products like Liver RX or Organ Shield can be beneficial. NAC, Fish Oil, Multivitamins, and OTC acne cleansers can help reduce potential side effects.†

How To Cycle HydroxyProgestin:

  • Dosage: 100–200 mg per day, split into two doses†
  • Cycle length: Short cycles of 3–4 weeks are preferred†

This approach helps maximize results while minimizing risks†


Dehydroepiandrosterone:

DHEA To Test

Other Names:
  • DHEA
  • Androstenolone
  • Prasterone
Popular Standalone Products:
Featured Blend Products:
Run Down:
  • Converts To Numerous Anabolic/Androgenic Hormones, Like Testosterone†
  • Could Slow Aging†
  • Improve Cognitive Function†
  • Improve Body Composition†
  • Boost Mood†
  • Improve Bone Density†

What Is DHEA?

DHEA is a hormone naturally produced by the adrenal glands. It plays a key role in making testosterone and estrogen.†

What To Expect From DHEA:

DHEA supplements can raise testosterone and estrogen levels. This makes them popular for anti-aging and hormone replacement therapy.†

Beyond hormones, DHEA affects:

  • Immune system†
  • Metabolism†
  • Mood regulation†
  • Cognitive function†

In prohormones, DHEA derivatives like 1-DHEA and 4-DHEA support muscle growth and strength.†

DHEA Side Effects:

DHEA is generally well-tolerated, but mild side effects can occur. This can include oily skin, acne, and increased hair growth in areas like the armpits and pubic region.†

High doses or long-term use may push testosterone and estrogen levels too high, causing adverse effects. These can include mood swings, cardiovascular complications, and hormonal imbalances.†

Treating Side Effects:

Most users don’t need additional on-cycle support. However, individuals experiencing adverse effects should consider consulting a healthcare professional. Additionally, monitoring hormone levels and adjusting your regimen can help reduce the risk of side effects.†

How To Cycle DHEA:

Doses of 25–50 mg per day are common for older adults.†

Cycle length and breaks depend on:

  • Individual goals†
  • Health status†
  • How your body responds†

Some users take intermittent cycles or periodic breaks to maintain effectiveness and prevent tolerance.†


3AD Dehydroandrosterol:

3AD to Test

Other Names:
  • 3AD
  • Dehydroandrosterol
  • Androst-5-ene-3a,17b-diol
  • 5-Androsten-3a,17b-diol
  • Androst-5-en-3a,17b-diol
  • 5-Androstenediol
Popular Standalone Products:
  • Mesotrope, by Dragon Pharma ~5 mg
  • 3-AD, by Enhanced Labs ~ 75mg
Featured Blend Products:
Run Down:
  • Increase Muscle Strength†
  • Dry, Hard Look†
  • May Boost Strength Of Other Compounds†

What Is 3AD?

3AD is a unique prohormone with a different biosynthesis pathway. Unlike most prohormones, it is not derived from dihydrotestosterone (DHT). Instead, it is made from DHA (dehydroandrosterone). This special pathway gives 3AD a distinct mechanism of action compared to other prohormones.†

DHA Explained:

DHA is a naturally occurring androgenic corticoid. It is mainly made from dehydroandrosterone and other steroid precursors like 5-androsten-3,17-dione. DHA has anabolic, androgenic, anti-estrogenic, and anti-cortisol effects. This makes it effective for muscle growth.†

DHA has about 43% of the androgenic activity of testosterone. This allows it to increase lean muscle mass by improving nitrogen retention and protein synthesis.†

DHA is versatile. It exists in esters, ethers, salts, and isomers, and is found in animal steroids, plant sterols, or extracts. When supplemented, it attaches to androgen receptors in muscle tissue. This supports anabolic and anti-catabolic responses, promoting muscle growth.†

What To Expect From 3AD:

Because 3AD comes from DHA, it is less likely to cause estrogenic effects compared to other prohormones.†

Users may see benefits such as:

  • Increased muscle strength†
  • Gains in lean muscle mass†
  • Enhanced muscle hardness†

It works well for both bulking and cutting cycles.†

Stacking 3AD:

  • For bulking: Combine 3AD with compounds like DHEA, Androsterone, Epiandro, or Arachidonic Acid to maximize muscle growth.†
  • For cutting: Stack 3AD with Epiandro Acetate, Androsterone Acetate, or Arimistane to maintain muscle while losing fat.†

3AD Side Effects:

Most users tolerate 3AD well. However, mild side effects can occur, including acne and joint dryness, especially on longer cycles.†

Treating Side Effects:

To reduce acne and joint issues, follow strategies similar to other prohormones. This may include topical acne treatments and joint supplements. Additionally, following a proper skincare routine to keep skin healthy and hydrated†

How To Cycle 3AD:

  • Dosage: Usually 25–60 mg per day, adjusted for weight, experience, and goals†
  • Cycle length: 6–12 weeks†
  • Breaks: At least 6 weeks between cycles for recovery and hormone normalization†

On-cycle support supplements are not required if taking 3AD alone. However, they are recommended when stacking to reduce side effects and provide full support.†

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Post Cycle Therapy (PCT):

After completing a prohormone cycle, starting Post Cycle Therapy (PCT) is essential. PCT helps restore hormonal balance and protects your hard-earned gains.†

During a cycle, external hormones can suppress natural testosterone production and increase estrogen. This imbalance may cause side effects like fat gain, testicular shrinkage, and low energy.†

Need more information on PCTs? Check out our PCT Guide!

Here’s what you need to know about PCT and some popular products to consider:

  1. Testosterone Restoration: After a cycle, natural testosterone levels drop while estrogen may stay high. PCT stimulates the body to restart testosterone production. This helps prevent muscle loss and other negative effects of low testosterone.†
  2. Estrogen Modulation: High estrogen can cause gynecomastia (male breast enlargement) and water retention. PCT includes compounds that regulate estrogen to avoid these side effects.†
  3. Liver Protection: Prohormones can stress the liver and kidneys. Many PCT products contain ingredients that support liver function, aiding detoxification and metabolism.†

What to look for in a PCT:

  • Testosterone repair: Ingredients like D-Aspartic Acid, Tribulus Terrestris, and Fenugreek Extract can help naturally boost testosterone production.†
  • Estrogen modulation:  Compounds such as Arimistane (Androsta-3,5-diene-7,17-dione) help control estrogen levels and reduce side effects.†
  • Liver Protection: Ingredients like Milk Thistle, NAC, and TUDCA support liver health and assist detoxification.†

Popular products:

  • Novedex XT (Gaspari Nutrition): Potent estrogen blocker that helps restore hormonal balance.†
  • Arimistane (Hi-Tech Pharmaceuticals): Aromatase inhibitor that prevents testosterone from converting to estrogen.†
  • Estrogenex (Hi-Tech Pharmaceuticals): Contains estrogen-modulating ingredients to prevent side effects and support testosterone.†
  • PCT V (Blackstone Labs): Supports testosterone production and helps restore hormonal balance post-cycle.†
  • Letro XT™(Blackstone Labs): Includes 3b-hydroxy-androsta-1,4,6-triene-17-one and 3b-hydroxy-androsta-4,6-diene-17-one. These ingredients reduce estrogen and support testosterone production.†
  • HellRaiser™ PCT (Innovative Labs): Blends ingredients to boost testosterone, regulate estrogen, and maintain overall hormonal balance.†

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Prohormone Stacks:

Prohormones can be cycled individually or combined into stacks to achieve specific goals. For example, the Blast Your Mass Stack features 1-Testosterone and Equipoise (formerly Equibolin).

hi-tech_pharmaceuticals_blast_your_mass_stack

Considerations for Stacking:

  1. Experience with Prohormones: Beginners may prefer single-prohormone cycles or pre-made blends for simplicity. This includes products like Helladrol or Monster Plexx. Meanwhile, more experienced users may prefer customized stacks for targeted results. Or, for more customization, you can try the Hi Tech Prohormone + Laxogenin Stack or First Time Cycle – Blackstone Labs Prohormone Stack.†
  2. Time: Stacking prohormones may need longer cycles and more comprehensive post-cycle therapy (PCT).
  3. Preference: Some users prefer the convenience of pre-made stacks, while others enjoy the flexibility of creating their own combinations based on their specific goals.
  4. Finances: Stacking prohormones can be more expensive than using a single compound. Therefore, budget considerations may influence stacking decisions.

We recommend a couple of different stack options, such as the Hi-Tech Pharmaceuticals ProHormone Stack, for more intermediate pro hormone users.

  • Bulking : 1-Andro + 4-Andro
  • Cutting: 1-Andro + 19-Nor-DHEA
  • Strength: 19-Nor-DHEA + 1,4 Andro

Dosing Recommendations:

  • Follow the directions on the product labels for dosing instructions. Typically, prohormones are taken orally with meals, and doses may be split throughout the day.
  • If a bottle recommends taking 2-4 tablets per day, you can divide the dosage, taking 1-2 tablets in the morning and 1-2 tablets in the evening.

If you prefer an all-in-one type of prohormones, an intermediate user could also use the products mentioned above. Or you could try products like Halodrol and Metha Quad Extreme.


For more advanced pro hormone users:

We have stacks already listed that you can purchase with all the items and PCT together.

Bulking Stacks

Cutting Stacks:

Strength Stacks:

PCT Stacks:

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Pro hormone Blends:

In addition to individual prohormones, prohormone blends offer unique compound combinations to target specific goals. Here’s a closer look at popular blends:

Anavar:Anavar Supplement Facts

Anavar is a popular prohormone blend. It helps stimulate ATP production, boosts energy levels, and enhances workout performance.† 

  • Increased ATP Production: Anavar helps drive ATP (adenosine triphosphate) into muscle cells. This provides a steady energy source during intense exercise, improving endurance and workout performance.†
  • Enhanced Recovery Times: By supporting ATP production and energy metabolism, Anavar may enhance recovery.†
  • Muscle Volume and Size: Anavar can increase muscle volume and size by boosting protein synthesis and nitrogen retention. Over time, this can lead to fuller, more defined muscles.†
  • Improved Strength: With increased ATP and muscle growth, Anavar also enhances strength and power output.†

How To Use Anavar By Hi-Tech Pharmaceuticals:

The manufacturer recommends taking three (3) tablets in the morning and three (3) tablets in the afternoon or evening. Do not exceed the recommended dosage, as Anavar is a potent anabolic agent.

Anavar Review By James: “Fast delivery Anavar is a good product I always order at least too cycle of this stuff because i know it work i generally order off of suppz bit this time i got it from same day supplement because the price was too good and the shipping was free thank you same day supplement”

Dianabol:Dianabol Supplement Facts

Dianabol is a prohormone blend that helps build lean muscle while preserving existing muscle mass and strength.† 

  • Lean Muscle Building: Dianabol is very effective at promoting lean muscle gains due to its anabolic properties.†
  • Preservation of Muscle Mass: In addition to building new muscle, Dianabol helps maintain the muscle you already have.†
  • Enhanced Strength: Dianabol boosts strength and power. Many athletes and bodybuilders use it to lift heavier weights and improve overall performance. Users often notice significant gains in lifting capacity and overall strength.†
  • Improved Recovery: Dianabol supports faster recovery between workouts. This reduces muscle damage and allows for more frequent, intense training sessions.†

How To Use Dianabol By Hi-Tech Pharmaceuticals:

The manufacturer recommends taking one (1) tablet three times daily with meals. This is important as the strength of this product can cause nausea if consumed without eating.

Dianabol Review By N/A : “First the basics…getting older is not a death sentence! After back surgery, started weight training and after great gains, at six months tried this product on the advice of a friend. Now about 10 days in and seeing results that, frankly, I didn’t expect at this age…more energy during my workouts, harder and thicker muscles and as an added bonus… significant lift to my libido which wasn’t even a problem…lol. Timely, fast delivery, good pricing structure and results…definitely will be a repeat buyer.”

Superdrol:Superdrol Supplement Facts

Superdrol is a strong prohormone. It is known for helping build lean muscle, improve muscle hardness, boost strength, and support better body composition.†

  • Lean Muscle Growth: Superdrol is very effective at supporting lean muscle growth.†
  • Muscle Hardness: A standout feature of Superdrol is its ability to improve muscle hardness and definition.†
  • Increased Strength: Many use Superdrol for its strength-boosting effects, making it easier to lift heavier weights and train harder.†

How To Use Superdrol By Hi-Tech Pharmaceuticals:

The manufacturer recommends taking one (1) tablet in the morning and one (1) tablet in the evening. Do not exceed two (2) per day.

Superdrol Review By Steven: “I took Superdrol for about a month. I’m 68! I saw results. I’m taking it again, for 2 months this time, along with Decabolin. Definitely helps add muscle.”

Winstrol:Winstrol Supplement Facts

Winstrol is a well-known product for building muscle, boosting strength, and improving appearance.† 

  • Increase Lean Muscle Mass: Winstrol helps you gain lean muscle without causing water retention or bloating.†
  • Boost Strength:  It is popular for improving strength, which is why many athletes and bodybuilders use it to enhance performance.†
  • Increase Hardness and Vascularity: A key feature of Winstrol is its ability to make muscles look harder and more defined. Users often notice denser muscles with more visible veins.† 

How To Use Winstrol By Hi-Tech Pharmaceuticals:

The manufacturer recommends taking one (1) tablet three times per day. Do not take more than four (4) tablets daily.

Winstrol Review By Daniel: “Felt the product working only after a few days and felt no side effects even after two weeks. Fantastic pump and strength gains.”

Sustanon 250:

Sustanon Supplement Facts

Sustanon 250 is a unique blend of testosterone esters. Each ester plays a role in supporting muscle growth, strength, energy, and libido:

  • Lean Muscle Gains: Sustanon 250 contains 4-Andro Propionate, Enanthate, Isocaproate, and Decanoate. Together, these compounds support optimal protein synthesis in the muscles. This leads to significant lean muscle growth and helps create a sculpted, defined physique.†
  • Strength Enhancement: By combining multiple testosterone esters, Sustanon 250 boosts strength and endurance. This helps users push past workout limits and achieve greater strength gains over time.†
  • Increased Libido: The balanced mix of testosterone derivatives supports sexual health. Users may notice higher libido, stronger sexual function, and improved performance.†
  • Elevated Energy Levels: Sustanon 250 enhances energy metabolism. This provides more vitality and stamina, allowing users to power through demanding workouts.†

How To Use Sustanon 250 By Hi-Tech Pharmaceuticals:

The manufacturer recommends taking one (1) tablet daily. Do not exceed two (2) tablets daily.

Sustanon 250 Review By A.D.: “Was a bit skeptical about this product’s claims. I was hoping for a mild bump. What I got was the closest results to being on without being on. Strength went through the roof by the second week and kept getting better as the cycle continued. Recovery was absolutely amazing as well. Now here’s where it gets even better, strength gains have stayed with me now three weeks post cycle. Will be back for more of this!”

Halodrol:

Halodrol Supplement FactsHalodrol provides a wide range of benefits that support muscle growth, strength, recovery, and performance:

  • Increased Strength: Halodrol may improve muscular strength. This allows users to lift heavier weights and complete more intense resistance training.†
  • Improved Recovery: Halodrol helps speed up recovery between workouts. Faster recovery reduces muscle fatigue and soreness. This allows users to train consistently, repair muscles more effectively, and lower the risk of overtraining injuries. Together, these effects support long-term progress and performance.†
  • Increased Energy: The unique blend of ingredients in Halodrol may boost energy levels. This provides stamina and endurance for challenging workouts.† 
  • Lean Muscle Mass: Halodrol is formulated to support lean muscle growth. At the same time, it helps reduce unwanted fat buildup, giving a harder, more defined physique.†
  • Libido Support: With testosterone-supporting properties, Halodrol may also enhance libido and sexual function.†

How To Use Halodrol By Hi-Tech Pharmaceuticals:

The manufacturer recommends one (1) tablet 30 minutes prior to training. On non-training days, take one (1) tablet in the morning or afternoon. Do not exceed two (2) per day.

Halodrol Review By Mikey: “Quality Product. My overall experience has been tremendous.”

Primobolan:Primobolan Supplement Facts

Primobolan uses its blend of ingredients to support muscle growth, strength, recovery, and performance.:

  • Increase Lean Muscle Mass: Primobolan contains 1-Andro, which helps increase lean muscle tissue.†
  • Improve Strength: With 1-Andro, Primobolan also boosts muscular strength. This allows users to lift heavier weights and complete more intense workouts.†
  • Enhanced Vascularity: The addition of 3B-Acetoxyandrost-5-en-17-one supports better blood flow and circulation. This may increase vascularity, giving muscles a sharper, more defined look with greater vein visibility.†
  • Increased Protein Synthesis: Primobolan includes 6-keto-(25R)-spirost-5-en-3beta-diol, which supports protein synthesis. This helps the body use protein more efficiently for muscle repair and growth. Faster recovery between workouts and better muscle regeneration allow users to maximize training.†
  • Improved Exercise Performance: 6-keto-(25R)-spirost-5-en-3beta-diol may also boost energy metabolism and endurance. This makes it easier to sustain high-intensity workouts for longer periods.†

How To Use Primobolan By Hi-Tech Pharmaceuticals:

The manufacturer recommends one (1) tablet three times per day. Do not take more than six (6) tablets daily.

Primobolan Review By Mary: “My brother is a pharmacist and recommended this for an intense workout and he is right! I am energized, focused and feel good after. I recommend this too.”

Halotestin:

Halotestin Supplement Facts

Halotestin is formulated with potent ingredients to deliver a range of performance-enhancing benefits tailored to support strength, muscle density, and libido:

  • Increase Strength & Power: Halotestin’s blend of ingredients supports increases in strength and power. By promoting anabolic processes, it enhances muscular strength and performance. This enables users to achieve new personal bests in their training endeavors.†
  • Improves Muscle Density: With 4-andro, Halotestin can improve muscle density. This results in a more defined and sculpted physique. This ingredient also helps develop lean muscle mass while reducing excess body fat. This results in enhanced muscle definition as well.†
  • Enhanced Libido: Halotestin’s formula may contribute to increased libido and sexual function.†

How To Use Halotestin By Hi-Tech Pharmaceuticals:

The manufacturer recommends taking one (1) tablet in the morning and one (1) tablet in the afternoon.

Halotestin Review By Trent: “My strength and size has been consistently going up week by week, while using Halotestin. My bench, squat and deadlift are consistently going up. I help but to believe Halotestin is doing wonders!”

Trenabol:

Trenabol Supplement Facts (1)

Often compared to trenbolone, Trenabol is designed with powerful ingredients that support lean muscle growth, strength gains, and a dry, defined look.†

  • Increase Lean Muscle Mass: Trenabol includes 3b-enanthoxy-19-nor-androst-4-ene-17-one (76 mg), a strong compound that helps build lean muscle. By supporting anabolic activity, it encourages the growth of dense muscle tissue. This leads to a more sculpted, muscular physique.†
  • Boost Strength: The formula is made to enhance strength levels, helping users push through training plateaus. By improving muscle function and making energy use more efficient, it allows for heavier lifts and greater strength.†
  • Zero Water Retention: Some prohormones can cause water retention, which leads to bloating or puffiness. Trenabol is formulated to promote dry, lean gains without that effect. This helps muscles look more defined and shows off muscle detail more clearly.†

Trenabol vs. Trenbolone:

While Trenabol is often compared to trenbolone because of their similar effects on muscle growth and performance, they are not the same. Here are the key differences:

Legality:

  • Trenbolone: A controlled substance and illegal anabolic steroid in many countries, including the U.S.†
  • Trenabol: Sold as a legal prohormone supplement. This offers a legal option for people who want similar benefits without the risks.††

Formulation:

  • Trenbolone: A synthetic anabolic steroid that directly mimics testosterone but with much stronger effects on androgen receptors.†
  • Trenabol: A prohormone that contains precursor compounds. Once taken, these convert into active hormones inside the body.†

Side Effects:

  • Trenbolone: Known for a higher risk of side effects because of its strong androgenic properties. Potential issues include acne, hair loss, prostate enlargement, cardiovascular risks, and suppression of natural testosterone production.†
  • Trenabol: May provide similar benefits with a lower risk of severe side effects. However, responses can vary, and some side effects may still occur depending on the individual.†

How To Use Trenabol By Hi-Tech Pharmaceuticals:

The manufacturer recommends taking one (1) tablet in the morning and one (1) tablet in the evening. Do not exceed two tablets daily.

Trenabol Review By Jake: “Strength has gone up while my weight has gone down. Definitely seeing the most definition I have ever had.”


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Wrapping Up!

This concludes our guide on popular prohormone compounds! Thank you for reading, and if there’s another product you’d like us to review, an ingredient that you think needs further elaboration or another blog idea you want to see in the future, send us an email!

Check out some of our other blogs!

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Prohormone Safety:

Ensuring the safety of pro hormone use is essential, and there are several key steps individuals should take to minimize risks:

  1. Pre-Cycle Blood Work: Before starting a pro hormone cycle, comprehensive blood work is essential to establish baseline levels of key biomarkers. This includes testosterone, estrogen, liver enzymes, and lipid profiles. The baseline data serves as a reference point for monitoring changes throughout the cycle. By monitoring changes early, you can detect any adverse effects sooner.†
  2. Consultation with a Physician: A medical professional can assess health status, evaluate potential risks, and provide personalized guidance based on medical history, health conditions, and other relevant factors.†
  3. Monitoring Effects: Throughout the cycle, diligent monitoring of the effects is crucial. This includes observing changes in muscle mass, strength, libido, mood, and energy levels, as well as any adverse reactions. Keeping a detailed log of symptoms and progress can help identify issues and inform decisions.†
  4. Adherence to Dosage and Cycling Protocols: Following recommendations on dosage and cycling protocols is essential for minimizing risks. †
  5. Post-Cycle Therapy (PCT): Implementing a comprehensive PCT regimen is crucial for restoring natural hormonal balance and minimizing potential side effects after completing a cycle. †

Warnings And Side Effects:

  • Age Restriction: These products are not for anyone under 18–21 years old. They are intended only for healthy adults who already follow a good diet and exercise program.
  • Medical Safety: Always talk to a doctor before using. Do not use if you have, or have a family history of, prostate problems, heart disease, low HDL cholesterol, or breast cancer. Stop use right away if you notice side effects like a fast heartbeat, dizziness, or vision problems.
  • Hormone-Related Risks: These supplements may cause acne, hair loss, irritability, or increased estrogen levels. In women, they may cause facial hair growth or voice deepening. In men, they may increase the risk of prostate issues.
  • Drug Testing & Sports: Ingredients in these products may be banned by some sports organizations and could lead to false positives on drug tests. Competitive athletes should check with their organization before use.
  • Use with Caution: Do not exceed the serving size. Taking more than recommended can cause serious health problems.
  • Other Warnings: Some products may be made on equipment that processes common allergens like eggs, wheat, or soy.
  • Not a Substitute: These products should not replace medical advice or treatment from your doctor.

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Disclaimer:

†PLEASE NOTE: The intention of the information provided is for reference only. Furthermore, we are in no way providing medical advice or instruction. Instead, the information provided in this guide/blog utilizes anecdotal information and available studies/reviews. While our goal is to maintain and display accurate information, we can’t guarantee it represents the latest product formulation or information. Therefore, please visit the manufacturer’s website if you have any concerns. Also, the information above does not represent our views here at Same Day Supplements. Instead, these are the views and information the manufacturers and users provide. The Food and Drug Administration has not evaluated these statements. Finally, these products aim not to diagnose, treat, cure, or prevent any disease or illness.

References:

Talib Ahmad - NASM Certified Nutrition Coach (CNC)

Talib is a NASM Certified Nutrition Coach (CNC) and has been a supplement and fitness enthusiast for over 10 years. He’s a passionate powerlifter who enjoys helping others with their supplement regimens and training programs to ensure they achieve the best performance for their goals.