Pro Hormones [What You Need To Know In 2019]

Share the joy
  • 1

Pro Hormones- What You Need To Know (Updated)

(Estimated reading time: 20 minutes, 26 seconds.)

Pro hormones have been around since 1996. However the type of pro hormones available then vs now are very different. This new generation of pro hormones have to comply with the laws set in 2004. This is to ensure they’re safe, effective, and legal. Before these laws, the old generation came with a heavier set of risks and side effects. Now the new generation isn’t completely void of side effects or risk. But it has been greatly minimized. Today we’re going to go over:

  • Common pro hormone compounds
  • Stacks/cycles,
  • Side effects,
  • And the importance of PCT’s (post cycle therapy).

If you don’t see a pro hormone you want us to go over, leave a comment below or send us an email.

Want to jump ahead? Click the links below to find the section you need.

pro hormones old vs new

What Are Pro Hormones_

What Are Pro Hormones?

Pro hormones are precursors for specific hormones. Which convert to become anabolic hormones. The resulting effects are seen through several pathways. But, generally the most important effects are on the body’s:

  • Androgenic,
  • Estrogenic,
  • And progestogenic receptors.

Like anabolic steroids, pro hormones are androgen agonists. A strong androgen receptor agonist will present effects related to testosterone. Some of these effects include increased:

  • Aggression, †
  • Sex drive, †
  • Muscle strength, †
  • Muscle mass, †
  • Muscles feeling denser and more solid † .
As well as heightened risk of side effects related to high androgen levels.

These can include but are not limited to: increased susceptibility to hair loss and acne.

Pro hormones also effect your estrogenic and progestogenic receptors. The effects on these receptors tend to be similar. Pro hormones that convert to estrogen and progesterone can increase mass and strength.

Although a lot of the mass gains are often lost. This is due to them being associated with water retention more than anything else. This conversion also comes with its own set of risks and sides. Estrogenic side effects include but are not limited to:

  • Increased water weight,
  • Increased susceptibility to fat gain,
  • And gynecomastia (swelling of the breast tissue in men).

You may hear of a pro hormone being androgenic or estrogenic, or even both. This is often based on their primary method of action. All pro hormones will have an androgenic effect to some level. Pro hormones can differ in their impact on other body systems.

Typically, strong androgens are useful for promoting strength gains. This is via the central nervous system (CNS) stimulation. A strong androgen would often be something similar in nature to Dihydrotestosterone (DHT). Furthermore, some will promote enhanced red blood cell production. Which is why users usually experience great pumps and vascularity.


What different

Whats different?

As we mentioned before, the pro hormones available today are different from those available before the US congress passed the Anabolic Steroid Control Act of 2004. The new generation of pro hormones have a better delivery system and absorption rate. This means its not as taxing on your liver.

  • Liposomal Delivery System:
    • Liposomal technology has been used in the medical field as a carrier for drugs. But only now has made its way into nutrition supplements. Liposomes have a hydrophobic core with a hydrophilic shell. This simultaneously protects the molecule from degradation, while allowing it be more soluble.
  • Cyclosome™ Delivery:
    • Cyclosome™ Technology is another liposomal delivery technology. This approach can be useful in increasing pro hormone solubility and vesicles stability. By controlling the in vivo fate of hydrophobic compounds and in avoiding burst release of pro hormones from the vesicles. This allows the ‘Trojan Horse’ to deliver pro hormones and testosterone boosters to the systemic circulation by the intestinal lymphatic route. Almost all previous Oral capsules and tablets manufactured to increase testosterone are involved in the “first pass affect”. This renders the active compounds virtually useless.

Common Compounds_

Common Compounds

There are a bunch of different compounds and different ways to stack them. This guide will be covering

  • Well known compounds,
  • Their other names,
  • Effects,
  • Side effects,
  • Stack-ability,
  • And what kind of cycle it would be better for.

pro hormones 1-andro


Other names :

  • 1-Androsterone / 1-Andro
  • 1-DHEA / 1DHEA
  • 1-Dehydroepiandrosterone
  • 1-androstene-3b-ol-17-one
  • 3b-hydroxy-5a-androst-1-en-17-one
  • 3b-hydroxy-androst-1-ene-17-one
  • 3-hydroxy-5-androst-1-en-17-one

Popular Products :

Run Down:

  • Dry, Lean Muscle Mass Gains†
  • Increased Strength†
  • No Bloating or Estrogen Activity†
  • Good for Stacking
  • Good for Cutting
  • Increase in Vascularity†
What is 1-Androsterone

1-Andro is a legal pro hormone that gets converted to the active steroid 1-Testosterone. 1-Andro goes through a two step conversion to get to the target hormone, 1-Test.

What to expect from 1-Androsterone

For starters, 1-Andro has research backing it up. Depending on the product you choose, you can expect different results. In general, 1-Andro is great for increasing lean muscle mass, strength, and aggression. 1-Andro is beneficial for bulking and cutting programs.

For bulking, we would recommend a product like 1-Testosterone. Because it has the highest amount of mg per tablet, you’re going to see the effects faster. For cutting, we would recommend 1-AD. The label states it has 75mg of 1-Andro, it has 75mg 1-Andro Decanoate, which yields 47 mg actual 1-Andro. The extra ester chain allows the 1-Andro to breakdown slower. This helps control hormonal spikes.

Also, it’s important to note these products contain other ingredients. Except for 1-Andro from Lg science. 1-Testosterone for example has grapefruit extract which will inhibit the breakdown of 1-Andro. 1-AD, however, contains laxogenin. If you’re not sure if you want to hop into the pro hormone game, laxogenin is another great option. Because it is a plant steroid, laxogenin isn’t hormonal. So women can also choose to supplement with it to improve strength, recovery, and joint pain.

But in this formula, you won’t really feel it. The more noticeable effect is the joint support. Chosen 1, from Blackstone labs, on the other hand is a blend. This blend contains both esters and unesterified 1-Andro/1-DHEA. So you’re kind of getting the benefits of both 1-Testosterone and 1-AD, but at a much lower dose.

Are there side effects with 1-Androsterone

Just like with any other pro hormone, there are side effects to consider and deal with. Some of the more typical side effects include; potential acne, hair loss, prostate enlargement, cardiovascular problems (such as high blood pressure), increased liver and kidney values, and testicular atrophy, among other things. Some individuals also noted after high doses of 1-Andro, they experienced low libido and lethargy.

However these side effects appear to go away after the cycle, during the PCT. Because 1-Andro seems to only effect androgenic receptors, the estrogenic sides aren’t expected. Also, side effects like acne and hair loss have a higher potential if you are already susceptible for it.

How To Deal With sides effects from 1-andro

We recommend taking a on cycle support supplement like Gear Support. Products like this are going to help cut the potential of side effects. You would take it with your chosen pro hormones and stop during your PCT.

For low libido you can try products like D-Aspartic Acid, Maca, Horny Goat Weed, or blends like Stamina Rx.

For your skin and hair care, we encourage you to take a multivitamin with B vitamins. You can also consider Fish Oil, Omega 3, or NAC, which have benefits for your whole body in addition to hair and skin. For acne and preventing acne, there are a ton of OTC cleansers you can try; look for ones with salicylic acid and/or benzoyl peroxide.

how to cycle 1-andro

1- Andro can be used for up to 8 weeks with a 4 week PCT. Each bottle typically contains enough for a 4 week cycle. So for an 8 week cycle you will need to purchase a second bottle.

pro hormones 4 androjpg


Other names:

  • 4-Androsterone / 4-Andro
  • 4-DHEA / 4DHEA
  • 4-Dehydroepiandrosterone
  • 4-androstene-3b-ol-17-one
  • 3b-Hydroxy-4-androsten-17-one
  • 3β-hydroxyandrost-4-en-17-one
  • 3β-hydroxy-D4-androsten-17-one

Popular Products :

Run Down:

  • Lean muscle gains†
  • Strength gains†
  • Increased sex drive & libido†
  • More energy†
  • Converts to testosterone
  • Helps accelerate muscle recovery†
  • Supports better overall mood†
  • Helps reduce muscle fatigue†
  • Increases protein synthesis†
what is 4-Androsterone

4- Andro is similar to 1-Andro, in that they both go through a two step conversion to become the target hormone. In 4-Andro’s case, that means converting to testosterone. Whereas 1-Andro converts to 1-Testosterone.

what to expect from 4-Androsterone

4-Andro is considered more of a wet gainer. Because it converts to testosterone there is a chance of an estrogen conversion. With products like this that mean there is going to be water retention. With that comes larger muscle mass gains and strength gains.

Due to the water retention, we would recommend 4-Andro for bulking. However it can be, and often is, used in stacks. Like with 1-Andro, different products and different mgs can have a different effects. Also like 1-Andro, the brands follow the same trend with the products. Blackstone’s Brutal 4ce is a blend of 4-Andro, Hi-Tech’s Androdiol has laxogenin, and LG’s 4 Andro is just 4-Andro.

What makes 4-Andro so different is that it converts to testosterone, the hormone, not another precursor. With that, gains come faster, recovery is faster, and some of the side effects from 1-Andro are avoided. Cycling with 4-Andro increase libido and doesn’t provide lethargy. Instead you can expect more of that Alpha-Male ecstasy. If you are looking to increase lean muscle mass, sex drive, energy, then 4-Andro is for you.

Are there side effects 4-Androsterone

Now because there is a chance for an estrogen conversion, you have the risk of those side effects. Those include increased water weight, increased susceptibility to fat gain, and gynecomastia. This is in addition to some of the more common side effects of pro hormones usage, potential acne, hair loss, cardiovascular problems (such as high blood pressure), and aggression. However because 4-Andro is not methylated, you don’t have to be concerned with liver toxicity.

How to deal with side effects from 4-Androsterone

To avoid the estrogen conversion, and risks it comes with, stack an aromatase inhibitor (estrogen blocker) in your cycle. You can also take it after during your PCT. When taken during a cycle, they can limit estrogen conversion. Taken after a cycle, they help prevent rebound gyno.

For the other side effects you can follow the same protocol as 1-Andro. NAC, Fish Oil, Multivitamins, and OTC acne cleansers. Because the 4-Andro is not methylated you do not need to take a on cycle support. However, if you still feel concerned you can take NAC or Milk Thistle.

how to cycle 4-Andro

4-Andro can be used for up to 8 weeks with a 4 week PCT. For beginners, you may want to opt for a shorter cycle to see how your body responds to the pro hormones. This can be 4 to 6 weeks on the pro hormones and a 4 week PCT.

pro hromones 19-nor-dhea


Other Names:

  • 19-Nor-DHEA
  • 19-Nor-Andro
  • 19 NorAndrosterone
  • 19 Nor Dehydroepiandrosterone
  • NorAndrost-4-ene-3b-ol, 17-one
  • 19-Norandrost-4-ene-17-one

Popular Products:

Run Down :

  • Good for Stacking
  • Hard, Dry Looking Physique†
  • Increase Strength†
  • Increase Lean Muscle Mass†
  • Does Not Aromatize to Estrogen†
  • Does Not Convert to DHT†
what is 19-Nor-4-Androstenediol

19- Nor-DHEA, like the other compounds we’ve discussed, is more of a prepro hormone. Through a two step conversion, 19- Nor-DHEA will ultimately convert to Nandrolone (Deca).

what to expect 19-Nor-4-Androstenediol

Unlike the previous compounds, there isn’t as much research to back up the benefits. However, users do claim to see strength gains and lean muscle mass gains. As always, results will vary. But we do recommend this pro hormone for people who are more susceptible for side effects. Nandrolone by nature isn’t as strong as testosterone. So for more experienced pro hormone users, you may not prefer this compound.

19- Nor-DHEA is the best choice for those looking to increase muscle growth and strength. While also accelerating fat loss. It has, however, earned a reputation for taking a long time to “kick in” and for suppressing natural testosterone.

We would recommend 19- Nor-DHEA for people looking to increase strength. But if you goal is more physique oriented, it could work well in a cutting stack as well. Keep in mind that Blackstone Lab’s product, Abnormal, features a blend and Hi-Tech’s product, Decabolin, is just 19- Nor-DHEA.


are there side effects 19-Nor

Like we mentioned before Nandrolone isn’t as strong as testosterone, so this means there’s a lower risk for side effects. Of the potential side effects, water retention is the most probable. Users have noted more water retention from 19- Nor-DHEA than 4-Andro.  Another common side effect was low libido.

how to deal with side effects from 19-Nor

You could tackle both of these sides by taking a estrogen blocker during your cycle. But for more libido support you can try D-Aspartic Acid, Maca, Horn Goat Weed, or blends like Stamina Rx also. And as always a PCT will need to follow your cycle.

Again there isn’t as much research on this compound. So if you’re experiencing other common sides (i.e. acne), you can refer to the other compounds with ways to control them. You don’t need to take an on cycle support but again for the extra conscious you can take NAC or Milk Thistle.

How to cycle 19-Nor-4-Androstenediol

19- Nor-DHEA can be used for up to 6 weeks(due to it suppressing natural testosterone) with a 4 week PCT. Again if you’re new to pro hormones, you may want to opt for a shorter cycle to test the waters.

pro hormones 1,4-Androstadienedione


Other Names:

  • 1,4 AD
  • 1,4-Andro
  • 1, 4-androstadiene-3, 17-Dione
  • 1,4-Androstadienedione

Popular Products:

  • Equibolin, By Hi-Tech Pharmaceuticals ~ 75mg

Run Down:

  • Increase Lean Muscle Mass†
  • Improve Recovery Time†
  • Increase Strength†
  • Increases Appetite†
  • Increases Energy†
what is 1,4-Androstadienedione

Like all the other products above, 1,4 AD is going to go through a two step conversion to get to the target hormone(steroid). In Equibolin’s case the starting compound is 3b-Hydroxy-1,4-Androstadien-17-one Undecanoate (1,4 DHEA). From 1,4 DHEA the compound will convert to 1,4 Andro then to Boldenone.

what to expect from 1,4-Androstadienedione

Boldenone is known to significantly increase appetite. For this reason alone we recommend Equibolin for bulking. In addition to the the increase in appetite, you could expect a increase in muscle mass and strength.

1, 4 Andro is an ideal option for those looking to increase mass without the degree of water retention often seen with 4-AD. Because 1,4 Andro is highly anabolic there is a low conversion rate to estrogen, though it is there. This estrogen is enough to ensure your cycle is relatively bloat-free, while still receiving some of the benefits associated with estrogenic conversion. Unlike with 4-AD, 1,4 Andro effects take longer (2-3 weeks) to show.

are there side effects with 1,4-Androstadienedione

Because 1,4 Andro is highly anabolic, the risk of developing side effects are low. However we would recommend Equibolin for more experienced users of pro hormones.

how to deal with the side effects from 1,4-Andro

An on cycle support is not needed because Equibolin is not methlyated but if you want to play on the safe side you can take NAC, Milk Thistle, or an actual on cycle support. The estrogen conversion is there so if you wanted to take an estrogen blocker that would help avoid any potential side effects.

how to cycle 1,4-Andro

You should start seeing results in 3-4 weeks of supplementation and you can take this product for up to 8 weeks with a 4 week PCT.

Epiandrosterone pro hormone


Other Names:

  • 3- hydroxy-androstane-17-one
  • trans-Androsterone
  • Isoandrosterone
  • 3-Epiandrosterone
  • Epi-Andro

Popular Products: 

Run Down:

  • Increase Lean Muscle Mass†
  • Improve Recovery Time†
  • Increase Strength†
  • Support Libido†
  • Increase Vascularity†
what is Epiandrosterone

Epi-Andro was first discovered in the early 30’s. It isn’t the most potent androgenic compound but it is a metabolite of DHEA. 

what to expect Epiandrosterone

Epi-Andro is a popular cutting pro hormone. With this you can expect dry, lean muscle gains and also an increase in vascularity and sex drive. Compared to other pro hormones available, Epi-Andro is more mild. But there are some acute stimulant effects, so if you wanted to take your dose as a ‘pre workout’, you can.

Currently the only singular product we carry with Epi-Andro is Epi-Andro 50 from Lg Science. However, this product is also featured in LG Science’s Cutting Andro Kit. The first ingredient in Epi-Andro 50 is Epicatechin. This is not a pro hormone although it is often featured in formulas designed for muscle growth.

Epicatechin is found in foods like green tea and dark chocolate. What it essentially does is inhibit Myostatin production. Myostatin is a type of protein called a myokine, which limits our level of muscle growth. By inhibiting this protein, we help promote muscle growth.

are there side effects with Epiandro

Fortunately, epiandrosterone doesn’t aromatize to estrogen. So epiandrosterone doesn’t cause many of the estrogen-related side effects that other compounds can cause. However there are some issues that may present during your cycle.

There may be an overproduction of DHT. This can cause your hair to become brittle and fried. This is particularly true if you are predisposed to hair problems or if you are getting male pattern baldness. There also is a potential for joint problems or discomfort with Epi-Andro.

how to deal with side effects from Epiandro

An on cycle support is not needed for Epi-Andro  but if you want to play on the safe side you can take NAC, Milk Thistle, or an actual on cycle support it wouldn’t hurt your muscle growth. Because there isn’t a conversion to estrogen you wont have to deal with these side effects. However for issues like joint pain you can considering taking a joint supplement like Osteo Bi Flex

how to cycle Epiandrosterone

 It’s generally recommended to use Epi-Andro for no longer than 6 weeks per cycle. That said, aside from the acute effects, it can take a while for the effects to build up in the body and you might not notice anything by just using it for a couple weeks. Follow up your cycle with a 4 week PCT.

HydroxyProgestins 5aOHP and 1,4 OHP


Other names:

  • 17beta {3ketoethyl}-androsta-1,4-diene-3-one, 17a-ol – 1,4 OHP
  • 5aOHP
  • 17beta {3ketoethyl}-androstane-3-one, 17a-ol – 5aOHP
  • 17beta {3ketoethyl}-androsta-1,4-diene-3-one, 17a-ol

Popular Products :

Run Down:

  • Dry, muscle gains †
  • Strength gains†
  • Increase appetite †
  • Converts to DHT †
  • Helps accelerate muscle recovery†
what is HydroxyProgestins

HydroxyProgestins are the newest class of pro hormones. They exhibit effects like 1-Testosterone or Boldenone which are for growth.

what to expect with HydroxyProgestins

Unlike DHEA pro hormones which work with 3bHSD or 17bHSD, progestins use an enzyme called 17,20 Lyase. Which cleaves the 17 position side chain into a keto group. Then into a hydroxyl which is the active steroid.

(chemical name: 17beta-{1-Ketoethyl}-androstane-3-one, 17a-ol)

5aOHP is an anabolic progestin that converts to stanolone. Which is better known as dihydrotestosterone or DHT for short.

It appears that progestin based hormones may act as natural myostatin inhibitors. While also adding to our natural androgen levels. Lastly it also may also increase transcription via increased messenger RNA activity.

This causes 5aOHP to act like Winstrol. Because it helps achieve a lean look and adds mass without aggression. But, there is one major difference between winstrol and 5aOHP. The latter one will not cause any hair loss that is commonly associated with the use of winstrol.

(chemical name: 17beta-{1-Ketoethyl}-androsta-1, 4-diene-3-one, 17a-ol)

1,4-OHP is a precursor to boldenone. Like equipoise, this particular pro hormone will increase appetite and will enhance recovery. Due to the appetite increase, 1,4-OHP is often used in a bulking stack. Where it will help build lean mass without adding significant water weight. This pro hormone is highly anabolic and mildly androgenic. Which will contribute to a nice increase in vascularity. Besides, it is also very easy on the joints.

are there side effects with HydroxyProgestins

As it does not convert to estrogen or progesterone, side effects related to those should not be an issue. Liver toxicity could be a concern though. It would be a good idea to take this product with something to support health liver function.

how to deal with side effects from HydroxyProgestins

To help support liver function you can take a product like Liver RX or Organ shield during or after your cycle. For the other side effects you can take NAC, Fish Oil, Multivitamins, and OTC acne cleansers.

how to cycle HydroxyProgestins

A good dosage would be 100-200 milligrams (mg) per day split into two separate doses. Many users agree that this compound is better suited short cycles of 3-4 weeks.



Post Cycle Therapy (PCT)

Post Cycle Therapy (PCT)

With any pro hormone you decide to supplement with you’re going to have to take a PCT. Keep in mind your testosterone and estrogen levels are a ratio, if one goes up the other will too. So when you’re cycle ends, you’re left with a surplus of estrogen. This is why its important to take a PCT.

When you come off cycle, your natural testosterone levels are extremely low, but your estrogen levels are high, comparatively. When you begin your PCT, you’re helping your body increase that natural testosterone level.  So taking products like estrogen blockers post-cycle help ensure that natural testosterone levels are restored. Ignoring this puts you at risk of losing the gains you made during your cycle. As a result you can gain fat, experience testicular atrophy, be lethargic, etc.

pro hormones pct

What to look for in a PCT

  • Testosterone repair
    • To ensure that the natural levels are restored as quickly as possible.
  • Estrogen modulation 
    • Counteract any gynecomastia that is lingering around as well as any excess estrogen and excess water.
  • Antioxidant and Liver Protection
    • Cleanse and rejuvenate the liver and kidneys to ensure they are working as much as possible to metabolize the exogenous testosterone.
  • Prolactin control

    • Used in combination with the Estrogen modulation for control of any changes to the pituitary gland.

Popular products:



All the pro hormones we went over can be cycled on their own or in a stack. When deciding to stack or not it really comes down to

  • Experience with pro hormones
  • Time
  • Preference
  • Finances

Beginners have the option of just using a pro hormone alone


using a blend like Helladrol or Monster Plexx.

Products like these have many pro hormones dosed at the optimal range for your desired cycle. We would recommend following the directions on the bottle in regards to cycle length.

For more intermediate pro hormone users there are a couple of different stack options we would recommend:

  • Bulking : 1-Andro + 4-Andro
  • Cutting: 1-Andro + 19-Nor-DHEA
  • Strength: 19-Nor-DHEA + 1,4 Andro

Again for dosing we would recommend sticking with the bottle directions. But make sure to separate your doses. If the bottle states to take 2-4 tablets a day, you can take 1-2 in the morning and 1-2 tablets in the evening, usually preferred with food. If you prefer to have a product with all the pro hormones already in each tablet, an intermediate pro hormone user could also benefit from the products listed above. Or you could try products like Halodrol and Metha Quad Extreme.

For more advanced pro hormone users:

We have stacks already listed that you can purchase with all the items and PCT together.

What to stack in a pro hormone cycle


There are a couple products mentioned in these stacks (and generally) that we haven’t gone over. So here’s a quick run down on what they do. These products can also be taken alone of stacked with each other.


  • Stimulates and Drives ATP into Muscle Cells†
  • Improved Recovery Times†
  • Improved Muscle Volume†
  • Increased Protein Synthesis†
  • Increase Muscle Size and Strength†


  • Builds Lean Muscle†
  • Preserve Muscle Mass & Strength†


  • Lean Muscle Growth†
  • Muscle Hardness†
  • Increased Strength†
  • Increased Protein Synthesis†
  • Reduces Body Fat†
  • Helps Nitrogen Retention†



You must get your blood work done before starting a cycle. This will help provide you a baseline of where you are naturally. Which will help keep track of how the pro hormones effect you. Every person’s experience with pro hormones can be different. It’s important to talk to your physician when you decide to run a cycle to make sure you can benefit from it. A lot of people avoid this and it’s simply not advisable nor is it worth the long-term risk.



†PLEASE NOTE: The intention of the information provided is for reference only. We are in no way providing medical advice or instruction. The information provide in this guide is based on anecdotal information and available studies/reviews. It is our goal to maintain and display accurate information. Yet, we can’t guarantee it represents the latest formulation of the product or information. If you have any concerns, please visit the manufacturer’s website. Also, the information above is not a representation of our views at Same Day Supplements. Rather, these are the views and information provided by the manufacturers and users. The Food and Drug Administration has not evaluated these statements. Finally, the intention of these products are not to diagnose, treat, cure or prevent any disease or illness.

Pro Hormones : Guide To Gains
  • Overall Review - 10/10