Cloma Pharma Fat Burner Guide (2026): How Asia Black, Black Spider, Methyldrene 25, Methyldrene Elite, and China White Compare
💪 Quick Comparison Takeaways
- Asia Black 25: highest listed synephrine, yohimbe, and cayenne. It’s the most heat-forward option on the label.†
- Black Spider 25: the most blend-driven option, built for experienced stimulant users who want more than a straight ECA-style profile.†
- Methyldrene 25: the most controlled daily option, with a listed ECA blend, 250 mg caffeine, and the lowest disclosed yohimbe at 9 mg.†
- Methyldrene Elite 25: the yohimbe-forward step up from Methyldrene 25, with 260 mg caffeine and 18.75 mg yohimbe in a shorter formula.†
- China White 25: the ECA-style option with rhodiola, irvingia, green coffee, olive leaf, raspberry ketone, and blend-listed stimulants.†
📖 Table of Contents
If you’re comparing ECA-style fat burners in 2026, you’re usually chasing the same thing: more energy and appetite control while calories are low. You also still need to sleep and get through work like normal.
These Cloma Pharma options share a similar stimulant backbone. So the real decision is what each one adds, and how predictable you need the day to be. Which one fits your training days, workdays, and stimulant tolerance best?
- What separates Asia Black, Black Spider, Methyldrene 25, Methyldrene Elite, and China White on the label and in real use.†
- Why the shared ECA-style core matters, plus what synephrine, yohimbe, cayenne, tea extracts, rhodiola, and irvingia add on top.†
- How I’d choose based on your goal first, then your stimulant tolerance, before you chase the strongest option.†
- The simplest way to dose and time these while keeping sleep realistic.†
- How to rotate them with pre-workouts and caffeine so total stimulants stay realistic.†
Quick Comparison Snapshot
At-a-glance: these are the label differences that actually change your day. The specific milligram comparisons below come from the Supplement Facts panels shown in each section.†
- Same ephedra-style dose across all five: each one includes 25 mg of an ephedra-style botanical per serving. That means you’re picking based on the add-ons, not “more ephedra.”†
- Caffeine is clustered: Methyldrene 25 lists 250 mg, and Elite lists 260 mg. The blend-driven options land around 250 to 265 mg, so yohimbe exposure and add-on stimulants are usually the bigger separator.†
- Yohimbe dose spread: yohimbe extract is listed at 9 mg in Methyldrene 25, 18.75 mg in Elite, and 25 mg in Asia Black. Black Spider and China White keep yohimbe inside blends.†
- Synephrine spread: Asia Black lists 60 mg synephrine, Methyldrene 25 lists 50 mg, and Elite lists 40 mg. Black Spider and China White keep bitter orange inside blends.†
Use-case matchups
Asia Black 25
Best for: cardio-heavy cuts where heat, energy, and appetite control are all priorities.†
Why it works: it pairs the highest disclosed synephrine and cayenne with the highest disclosed yohimbe extract in the group. That’s why it reads as the most heat-forward label.†
Better fit elsewhere: if you want a calmer daily option, start with Methyldrene 25. That’s also the easier move if higher-yohimbe formulas usually hit you too hard.†
Black Spider 25
Best for: experienced stimulant users who want a layered, blend-driven formula.†
Why it works: it stacks PEA, theobromine, tea extracts, yohimbe, and bitter orange around the ECA-style base for a more “stacked” day.†
Better fit elsewhere: if you want every major stimulant amount itemized before you commit, choose Methyldrene 25, Elite, or Asia Black. Those give you clearer numbers.†
Methyldrene 25
Best for: daily cuts where consistency and dose clarity matter more than chasing the most potent label.†
Why it works: it keeps the ECA-style base strong while using the lowest disclosed yohimbe in the lineup, plus a clearly listed support system.†
Better fit elsewhere: if you already know you want more yohimbe or more “heat,” Elite, Asia Black, or Black Spider will fit that better.†
Methyldrene Elite 25
Best for: people who tolerate yohimbe well and want more of it than Methyldrene 25 provides.†
Why it works: it doubles yohimbe versus Methyldrene 25. It also stays more direct and shorter than Asia Black.†
Better fit elsewhere: if you want the lower-yohimbe routine of Methyldrene 25, or you want the higher synephrine and cayenne of Asia Black.†
China White 25
Best for: people who want an ECA-style option that also leans into fatigue and diet-support herbs.†
Why it works: its catalyst blend brings rhodiola, irvingia, green coffee, olive leaf, and raspberry ketone into the same formula as the ECA-style base.†
Better fit elsewhere: if you want exact yohimbe and synephrine numbers before you commit, China White keeps both inside blends.†
Ingredient Breakdown
Quick clarification: these labels look similar at first because they share the same ECA-style idea. The real split comes from yohimbe, synephrine, cayenne, caffeine sources, and whether the formula hides big drivers inside blends.†
Start with the shared ECA-style base
ECA stack is shorthand for ephedrine, caffeine, and aspirin. These Cloma formulas don’t use pharmaceutical ephedrine. They use an ephedra-style botanical plus caffeine and a salicin source from white willow.†
A 12-week randomized, double-blind, placebo-controlled trial looked at an herbal formula that contained ephedrine alkaloids, caffeine, and other ingredients. The active group lost more weight than placebo, which helps explain why this style of formula became part of the category.† (1)
A DARE/AHRQ evidence review found ephedrine and ephedra promoted modest short-term weight loss. The same review also linked ephedra or ephedrine with caffeine to a higher risk of heart palpitations and psychiatric, autonomic, or upper-GI symptoms. So the “ECA-style” label should read as useful for some people, but also more demanding.† (2)
Practical point: every option here includes 25 mg of an ephedra-style botanical per serving. The source is either Ephedra viridis or mormon tea. That means you’re not picking a winner based on “more ephedra.”†
Caffeine sets the floor
Caffeine is the baseline energy driver across the lineup. It’s a stimulant found in coffee, tea, energy drinks, guarana, and kola nut. It can support alertness and training output, but higher totals can disturb sleep and bring on jitters or anxiety.† (3)
Methyldrene 25 lists 250 mg. Elite lists 260 mg. Asia Black lands around 250 mg from caffeine anhydrous plus guarana, and Black Spider lists about 265 mg total. China White lists 250 mg in its ECA blend. Since those numbers are close, the “day-to-day intensity” usually comes from yohimbe exposure and the extra add-ons.†
Synephrine and yohimbe split
p-Synephrine is a bitter orange compound that fits best in a cardio and training context. Human exercise research reports that acute p-synephrine can increase fat oxidation during cycling. That’s why it shows up in thermogenic labels.† (4) A full-text review also summarizes similar findings in elite cyclists, while noting that more research is needed for long-term fat-loss outcomes.† (5)
That’s why Asia Black leads the itemized group at 60 mg, Methyldrene 25 follows at 50 mg, and Elite lists 40 mg. Black Spider and China White include bitter orange inside blends, so you can’t compare the dose directly.†
Yohimbe is the more personal tolerance check. A review of yohimbine research summarizes a soccer-player trial where body-composition changes showed more promise than performance changes. That’s why I don’t treat it like a guaranteed fat-loss switch.† (6)
For safety context, NCCIH links yohimbine with side effects like blood pressure issues, fast heart rate, and anxiety. That’s why this ingredient changes the whole day for some users.† (7)
On the itemized labels, Methyldrene 25 is the most controlled at 9 mg, Elite steps to 18.75 mg, and Asia Black goes to 25 mg. Black Spider and China White keep yohimbe in blends, so you judge them by the whole build instead of one number.†
Cayenne, evodia, tea extracts
Cayenne is part of the “heat” story, but it’s not the whole story. I treat it as a feel cue, then I look back at caffeine, synephrine, and yohimbe for the big drivers.†
Asia Black lists 40 mg cayenne, Methyldrene 25 lists 35 mg, and Elite lists 25 mg. Black Spider keeps cayenne inside a blend, and China White doesn’t list cayenne. Evodia is 5 mg in Asia Black and also appears inside Black Spider’s ignition blend.†
For tea extracts, human research has looked at green tea catechins, caffeine, energy expenditure, and fat oxidation. Another study found green tea plus guarana increased 24-hour energy expenditure, even though it didn’t increase lipid oxidation.† (8) (9)
That’s why Asia Black leans on green tea and guarana. Methyldrene 25 adds green tea. Black Spider stacks green tea, black tea, guarana, and yerba mate inside a blend. The tea layer is a big reason Black Spider reads “more stacked” than a straight caffeine plus synephrine build.†
Focus support paths
These aren’t pure nootropic formulas, but the support ingredients still matter when a diet makes you mentally flat. A controlled study on Panax ginseng G115 reported improved cognitive performance during sustained mental work. That fits why it shows up beside heavy stimulants.† (10)
A double-blind crossover study found rhodiola rosea helped mental performance during night duty in physicians. That’s why I treat rhodiola as fatigue support instead of “more stimulant.”† (11)
China White uses rhodiola, so its “focus” angle is more about pushing through fatigue than pushing more stimulant energy. Methyldrene 25 and Elite list 50 mg ginseng, Asia Black lists 20 mg, and Black Spider keeps ginseng inside a blend.†
China White catalyst blend
China White separates itself with a 470 mg catalyst blend. A review on Irvingia gabonensis looked at changes in body weight, waist size, and other body measurements. That’s why it fits the measurement-focused side of the formula.† (12) A green coffee extract review also evaluated effects on body weight, waist size, and other body measurements in adults.† (13)
So China White still hits the ECA-style base, but it also tries to support diet consistency with fatigue and body-measurement context ingredients. That’s a different “why” than a label built mainly around listed yohimbe and synephrine numbers.†
What matters less
Chromium picolinate gets attention in weight-loss marketing, but it shouldn’t decide this comparison. A Cochrane review found chromium picolinate’s effect on weight loss was small and of questionable clinical importance. That’s why I treat it as a minor add-on here.† (14)
The same goes for very low-dose extras. Asia Black lists ginger, bladderwrack, N-acetyl-L-carnitine, L-tyrosine, evodia, yerba mate, and kola nut at 1 to 10 mg. Black Spider includes several similar botanicals inside its ignition blend. Those ingredients add flavor to the formula, but your decision still comes back to caffeine, synephrine, yohimbe, and cayenne.†
Coach’s insight: if all five look strong, I start with yohimbe. Then I check synephrine and cayenne. Last, I decide if I want the clarity of itemized amounts, or I’m fine with a blend-driven label.†
Asia Black 25
Asia Black 25 is the “turn it up” choice when your cut already has structure, steps, training, and meals are dialed in. It’s not just caffeine. It’s a clearly itemized combo of caffeine, Ephedra viridis, white willow, synephrine, yohimbe, and cayenne, plus smaller add-ons like tea extracts and botanicals.†
What I like about Asia Black is you can actually see the pressure points. You’re not guessing where the intensity comes from. You can point to the synephrine, yohimbe, and cayenne numbers and decide if that fits your routine.†
What you may notice first
Energy: it starts with 200 mg caffeine anhydrous, then adds guarana standardized for caffeine and a small kola nut extract. That’s how the label lands near ~250 mg total caffeine.†
Heat and training tie-in: citrus aurantium brings the synephrine piece, and the exercise data on p-synephrine fits best when you’re pairing the formula with cardio, steps, or training.† (4) (5)
Yohimbe check: at 25 mg of yohimbe bark extract standardized to 8% yohimbine, this is the part most likely to make someone either love it or hate it.† (7)
Support ingredients worth reading
- Green tea plus caffeine sources: green tea and guarana show up together for a reason. Research found green tea plus guarana increased 24-hour energy expenditure, which helps explain that pairing in thermogenics.† (9)
- Panax ginseng: included for cognitive performance support during sustained mental work, which matters when dieting makes you mentally flat.† (10)
- Ginger and bladderwrack: these sit in the “small support” category here. Ginger is traditionally used for digestive comfort, while bladderwrack is a seaweed tied to naturally occurring minerals such as iodine.† (15) (16)
- N-acetyl-L-carnitine and L-tyrosine: listed at 5 mg each, so I treat them as background support instead of key drivers.†
How to take it
Serving size: 1 capsule.
Schedule: 1 capsule with breakfast, then 1 capsule with lunch. Don’t exceed 2 capsules daily, and don’t take it within 6 hours of bedtime. Caffeine taken 6 hours before bed can still disrupt sleep. Timing is the simplest performance hack here.† (17)
First-week tip: start with 1 capsule for the first 3 days, then move to the full 2-capsule daily schedule if your day stays steady. This is the one place you’ll see me say it: assess tolerance once, then keep the plan consistent.†
Full label details (per 1 capsule)
Asia Black 25 Supplement Facts
Vitamins and mineral: Vitamin B6 (as pyridoxine HCl) 500 mcg, Vitamin B12 (as cyanocobalamin) 150 mcg, Chromium (as chromium picolinate) 30 mcg.†
Caffeine and ECA-style core: Guarana seed extract (22% caffeine) 227 mg, caffeine anhydrous 200 mg, white willow bark extract (25% salicin) 100 mg, Ephedra viridis powder 25 mg.†
Thermogenic and yohimbe drivers: Citrus aurantium fruit extract (30% synephrine) 60 mg, cayenne pepper (40,000 HU) 40 mg, yohimbe bark extract (8% yohimbine) 25 mg.†
Tea and botanical supports: Green tea extract (95% polyphenols, 45% EGCG) 20 mg. Panax ginseng root extract (4% ginsenosides) 20 mg. Ginger root powder 10 mg. Bladderwrack powder 10 mg.†
Trace add-ons: N-Acetyl-L-carnitine 5 mg and L-Tyrosine 5 mg. Evodia rutecarpa fruit extract (10% evodiamine) 5 mg. Yerba mate leaf powder 3 mg and Kola nut extract (10% caffeine) 1 mg.†
Total caffeine: ~250 mg.†
Shop for Asia Black 25.
Black Spider 25
Black Spider 25 is the one I reach for when straight caffeine feels one-note. It uses multiple stimulant and thermogenic angles in one cap. That can make the day feel more “stacked” than a basic ECA-style profile.†
This is also the most blend-driven label in the group. That’s fine if you like the ingredient mix. But it’s not the one to pick if you only feel comfortable when yohimbe and bitter orange are fully itemized.†
Energy and drive ingredients
- Caffeine anhydrous: the label lands near ~265 mg total caffeine, so plan your coffee and pre-workout around that.†
- Tea extracts plus guarana and yerba mate: this is the “tea plus caffeine” layer. A controlled study found green tea plus guarana increased 24-hour energy expenditure, which is a realistic explanation for why this combo is popular in thermogenics.† (9)
- Phenylethylamine HCl (PEA): PEA is a trace amine. Think of it as a small signaling compound tied to monoamine pathways, the same broad system involved in alertness and mood. That helps explain why it appears in formulas aimed at drive.† (18)
- Theobromine: a cocoa methylxanthine that can change the energy profile next to caffeine.† (19)
Heat and appetite drivers
- Bitter orange: synephrine fits best as a training and cardio support ingredient, since exercise studies show higher fat oxidation after acute p-synephrine.† (4)
- Yohimbe: this is the ingredient most likely to define tolerance, NCCIH links it with blood pressure changes, tachycardia, and anxiety in some users.† (7)
- Cayenne and evodia: these are included for warmth and “thermogenic” sensation. One human study reported that capsaicin and evodiamine did not increase energy expenditure and fat oxidation. So I treat them as sensation cues, not the main fat-loss engine.† (20)
Who it fits
Black Spider fits when you want energy, drive, warmth, and appetite control all in the same day, and you’ve already used stronger thermogenics. The appeal is the combo effect from caffeine, PEA, theobromine, tea extracts, yohimbe, and bitter orange working together.†
How to take it
Serving size: 1 capsule.
Schedule: 1 capsule with breakfast, then 1 capsule with lunch. Don’t exceed 2 capsules in 24 hours. Don’t take it within 6 hours of bedtime.† (17)
Full label details (per 1 capsule)
Black Spider 25 Supplement Facts
Vitamins and mineral: Vitamin B6 (as pyridoxine HCl) 2 mg, Vitamin B12 (as cyanocobalamin) 6 mcg, Chromium (as chromium picolinate) 30 mcg.†
ECA Proprietary Blend: 300 mg including caffeine anhydrous, white willow bark extract (25% salicin), Ephedra viridis leaf (25 mg).†
Stimulating Thermogenic Ignition Blend: 346 mg total.†
Blend stimulant and thermogenic pieces: Citrus aurantium extract (30% synephrine), phenylethylamine HCl, yerba mate extract, guarana seed extract, yohimbe plant extract (8% yohimbine), cayenne pepper (40,000 HU).†
Blend tea and botanical supports: Green tea extract (95% polyphenols), black tea extract, Panax ginseng root extract (4% ginsenosides), ginger root powder, bladderwrack powder, theobromine, Evodia rutaecarpa extract.†
Total caffeine: ~265 mg.†
Shop for Black Spider 25.
Methyldrene 25
Methyldrene 25 is the easiest daily-use fit in this lineup. It’s still a stimulant-heavy ECA-style formula. But it’s more organized, and the key numbers are easier to plan around.†
You get a 375 mg ECA blend, plus a 298 mg support system. That setup keeps synephrine strong while holding yohimbe lower than the other itemized options. That’s the main reason it’s easier to repeat day to day.†
The ECA blend
- Caffeine anhydrous (250 mg): a clear number you can plan around, especially if you’re the type who accidentally stacks coffee and pre-workout.†
- White willow (100 mg): the salicin source in the ECA-style setup, it’s part of the traditional “ECA-like” pattern.†
- Ephedra viridis (25 mg): this is the ephedra-style botanical. Human research on an ephedra-and-guarana supplement reported persistent increases in heart rate and blood pressure, so this category deserves respect.† (21)
The support system
- Synephrine (50 mg): strong enough to matter, and it fits best when you’re active since p-synephrine increased fat oxidation in exercise studies.† (4)
- Panax ginseng (50 mg): included for focus support, since a controlled trial found single-dose ginseng improved cognitive performance during sustained mental activity.† (10)
- Cocoa fruit extract (35 mg): brings theobromine, which can change the stimulant profile next to caffeine.† (19)
- Cayenne (35 mg) and green tea (25 mg): included for warmth and tea polyphenol context. A study found green tea plus guarana increased 24-hour energy expenditure.† (9)
- Ginger (38 mg) and cactus cladodes (35 mg): these read like meal-time support. Ginger fits the digestive-comfort tradition, and Opuntia-derived cactus fiber has been studied in weight-management contexts.† (22)
- Yohimbe (9 mg) and 5-HTP (1 mg): 9 mg is the lowest disclosed yohimbe in this group, which is why it’s easier to keep consistent. The 1 mg 5-HTP is too small to treat mood support as the main story.† (7)
How to take it
Serving size: 1 capsule.
Schedule: 1 capsule with breakfast, then 1 capsule with lunch. Don’t exceed 2 capsules in 24 hours. Don’t take it within 6 hours of bedtime.† (17)
Full label details (per 1 capsule)
Methyldrene 25 Supplement Facts
Vitamins and mineral: Vitamin B6 (as pyridoxine HCl) 2 mg, Vitamin B12 (as cyanocobalamin) 6 mcg, Chromium (as chromium picolinate) 30 mcg.†
ECA Blend: 375 mg including caffeine anhydrous 250 mg, white willow bark powder (25% salicins) 100 mg, Ephedra viridis leaf 25 mg.†
Methyldrene Fat-Burning Support System: 298 mg total.†
Thermogenic supports: Citrus aurantium extract (30% synephrine) 50 mg. Cocoa fruit extract (20% theobromine) 35 mg. Cayenne pepper (40,000 HU) 35 mg. Green tea extract (95% polyphenols) 25 mg.†
Botanical and yohimbe supports: Panax ginseng root extract (4% ginsenosides) 50 mg. Ginger root powder 38 mg. Cactus cladodes (Opuntia ficus indica) powder 35 mg. Yohimbe bark extract (8% yohimbine) 9 mg. Griffonia seed extract (5-HTP) 1 mg.†
Shop for Methyldrene 25.
Methyldrene Elite 25
Methyldrene Elite 25 is the cleanest “yohimbe step up” from Methyldrene 25. Caffeine barely changes, but yohimbe jumps from 9 mg to 18.75 mg, and that’s what typically changes the day.†
The ingredient list is shorter than Asia Black, so Elite reads more direct. You get caffeine, Ephedra viridis, white willow, yohimbe, synephrine, cayenne, cocoa, and ginseng. A handful of smaller add-ons sit around that core.†
What changes the day
- Caffeine (260 mg): baseline energy stays close to Methyldrene 25, so caffeine isn’t the main separator here.†
- Yohimbe (18.75 mg): the big move, and the reason Elite exists for people who already know yohimbe works for them.† (7)
- Synephrine (40 mg): fits best with activity and training days since exercise studies show higher fat oxidation after acute p-synephrine.† (4)
- Cayenne (25 mg): warmth cue alongside the stimulant drivers.†
Support add-ons
- Panax ginseng (50 mg): focus support that matters when you’re dieting and mentally dragging.† (10)
- Cocoa extract (25 mg): theobromine source that can change how the caffeine hits.† (19)
- MCT powder (25 mg): MCT means medium-chain triglyceride, a type of fat often used in supplement formulas for quick-fuel positioning. Here, it reads as a small support add-on beside the stronger stimulant pieces.†
- Bauhinia purpurea (10 mg): Bauhinia is a plant add-on. The research I found is early and preclinical, with lipid and body-weight marker data in a rat model, so I’d keep the wording light.† (23)
- Bacopa monnieri (5 mg): bacopa is an herb most people recognize from memory and focus formulas. A systematic review of randomized human trials evaluated Bacopa for cognitive performance. That’s why its role in Elite fits the focus-support side of the label. At 5 mg, it reads as a light focus cue beside ginseng and stimulants.† (24)
- Black pepper extract (5 mg): black pepper supplies piperine, which is commonly used in formulas for absorption support.† (25)
How to take it
Serving size: 1 capsule.
Schedule: 1 capsule with breakfast, then 1 capsule with lunch. Don’t exceed 2 capsules in 24 hours, and keep it at least 6 hours away from bedtime.† (17)
Full label details (per 1 capsule)
Methyldrene Elite 25 Supplement Facts
Vitamins and mineral: Vitamin B6 (as pyridoxine HCl) 2 mg, Vitamin B12 (as cyanocobalamin) 6 mcg, Chromium (as chromium picolinate) 30 mcg.†
ECA-style core: Caffeine anhydrous 260 mg, white willow bark extract (25% salicin) 50 mg, Ephedra viridis leaf powder 25 mg.†
Thermogenic and yohimbe drivers: Citrus aurantium extract (30% synephrine) 40 mg. Cayenne pepper (40,000 HU) 25 mg. Cocoa fruit extract (20% theobromine) 25 mg. Yohimbe bark extract (8% yohimbine) 18.75 mg.†
Support add-ons: Panax ginseng root extract (4% ginsenosides) 50 mg, MCT oil powder 25 mg, Bauhinia purpurea powder 10 mg, Bacopa monnieri extract 5 mg, black pepper extract 5 mg.†
Shop for Methyldrene Elite 25.
China White 25
China White 25 is the one I talk through when someone wants ECA-style energy, but they also want a bigger diet-support herb layer around it. You still get caffeine, mormon tea, and white willow, plus yohimbe and bitter orange inside the blend. Then the catalyst blend adds rhodiola, irvingia, green coffee, olive leaf, winged treebine, and raspberry ketone.†
That mix matters because it changes what you’re buying it for. Asia Black and Elite are easier to explain as “numbers-first thermogenics.” China White is more like energy plus a broader herb blend for diet weeks that feel grindy.†
Stimulant base
- Caffeine, guarana, mormon tea, white willow: the ECA-style setup. Day to day, it’s a daytime formula, and timing is the biggest win.†
- Yohimbe plus bitter orange: synephrine has exercise data tied to fat oxidation, and yohimbe is the ingredient most likely to define tolerance.† (4) (7)
Catalyst blend highlights
- Rhodiola: the fatigue support herb. In a double-blind crossover study, rhodiola improved mental performance in physicians during night duty, which fits the “push through diet fatigue” use case.† (11)
- Irvingia gabonensis: a meta-analysis evaluated irvingia for changes in body weight, waist size, and related body measurements. That’s why it shows up in weight-management blends.† (12)
- Green coffee: a meta-analysis evaluated green coffee extract for effects on body weight, waist size, and other body measurements. That fits the measurement side of this blend.† (13)
- Olive leaf: a randomized controlled trial paired olive leaf extract with a calorie-restricted diet. The trial reported reductions in body weight and fat mass in obese women, which fits the diet-support context here.† (26)
- Winged treebine (Cissus quadrangularis): included as part of the broader metabolic-support story. A study using a Cissus formulation reported weight loss and metabolic syndrome marker changes.† (27)
- Raspberry ketone: raspberry ketone is an aromatic compound associated with raspberries. Here, it sits with irvingia, green coffee, olive leaf, and Cissus on the diet-support side of the catalyst blend.† (28)
How to take it
Serving size: 1 tablet.
Schedule: 1 tablet with breakfast, then 1 tablet with lunch. Don’t exceed 2 tablets daily. Keep it at least 6 hours away from bedtime.† (17)
Full label details (per 1 tablet)
China White 25 Supplement Facts
Mineral: Calcium (from calcium carbonate) 75 mg.†
ECA Proprietary Blend: 375 mg including caffeine anhydrous, white willow bark extract, mormon tea leaf powder.†
China White Energy & Thermogenic Catalyst Blend: 470 mg total.†
Blend botanicals: Winged treebine stem, leaf and flower extract, Irvingia gabonensis seed extract, rhodiola root extract, green coffee bean extract, olive leaf extract, raspberry ketone.†
Blend stimulant-adjacent ingredients: Yohimbe bark extract, guarana seed extract, bitter orange fruit extract.†
Shop for China White 25.
How They Compare By Effect
I narrow this choice by the part of cutting that’s hardest for you right now. That keeps you from buying the most intense label when what you needed was simply consistency.†
- Routine consistency: Methyldrene 25 is the simplest to repeat because key numbers are visible and yohimbe is lowest at 9 mg.†
- Heat and cardio push: Asia Black is the strongest listed heat profile. It leads the itemized group in synephrine (60 mg), yohimbe (25 mg), and cayenne (40 mg).†
- Yohimbe step up: Methyldrene Elite is the direct move when Methyldrene 25 feels right, but you want more yohimbe with the main amounts still listed.†
- Layered energy and drive: Black Spider is the blend-driven “stacked” experience, using caffeine plus PEA, theobromine, tea extracts, yohimbe, bitter orange, cayenne, and evodia.†
- Diet-support herbs: China White adds rhodiola, irvingia, green coffee, olive leaf, cissus, and raspberry ketone alongside the ECA-style base.†
Rule I use with clients: pick the formula that fits the day you can repeat. A burner that supports a whole week of training, meals, and sleep will beat the one that only feels “strong” on day one.†
Can You Use Them Together
You generally shouldn’t stack two of these on the same day. They share the same ECA-style core. Doubling up can raise the side-effect risk, especially when total caffeine gets too high.† (29)
- Rotate, don’t stack: if you want variety, rotate in blocks, for example a few weeks on one formula, then switch.†
- Keep your pre-workout stim-free: if you train later, a stimulant-free pre-workout is the simplest way to avoid accidental caffeine overload.†
- Pick one caffeine source: if you’re using an ECA-style fat burner, keep coffee and energy drinks out of the plan at first. Extra caffeine can make jitters, headaches, and poor sleep more likely.† (29)
FAQ
I already drink coffee in the morning. Do I need to change that?
I’d plan on changing it, at least at first. These formulas already sit around 250 to 265 mg caffeine per serving. Extra coffee can turn a usable day into jitters, headaches, or poor sleep. Decaf keeps the ritual without stacking stimulants.† (29)
I train after work. Can I still use one of these?
These work best as morning or early-day formulas. If you train later, keep your pre-workout stimulant-free. Keep your second serving far from bedtime, too. Caffeine taken even 6 hours before bed can reduce sleep, so timing matters more than squeezing in another cap.† (17)
What if yohimbe usually makes me feel awful?
This category likely isn’t your move. All five include yohimbe or yohimbe extract, and NCCIH links yohimbine with side effects like anxiety and rapid heart rate in some people. Methyldrene 25 gives the most yohimbe control because it lists the lowest disclosed amount, but it still contains yohimbe.† (7)
How do I know if a formula is too much?
Watch the boring signs first: worse sleep, higher resting heart rate, more anxiety, nausea, or shaky workouts. Those signs mean lower the dose, stop use, or pick a more controlled option. Chest pain, faintness, shortness of breath, severe headache, or an abnormal racing heartbeat are stop-use signals.† (30)
Do I need the second serving?
No. Treat the second serving as optional. If one morning serving helps your energy and appetite without wrecking sleep, that’s usually the better routine. More stimulant doesn’t automatically mean more progress.†
What if my weight loss stalls while I’m using one?
Don’t assume the answer is “stronger fat burner.” Check calories, protein, steps, training, sleep, and weekend intake first. These can support a cut, but they can’t replace the plan that creates the deficit.†
Can I switch from one Cloma fat burner to another?
Yes, switch for a clear reason. Move down if sleep or anxiety becomes a problem. Move up only if the current formula feels manageable. Know what changes first: more yohimbe, a more blend-driven stimulant stack, or a hotter synephrine plus cayenne profile. Don’t stack two together in the same day.†
Side Effects And Warnings
These are stimulant-heavy formulas, so the goal isn’t “take more and hope for more.” Your win is a productive day with appetite control, training output, and sleep that still happens.†
Normal stimulant reactions
- Possible side effects: jitters, nausea, headache, faster heart rate, elevated blood pressure, sweating, anxiety sensations, and insomnia.† (29) (7)
- When yohimbe is the limiter: shakiness, cold sweats, and panic-like sensations are reasons some people stop using this category.† (7)
Stop-use and avoid-use notes
- Stop use immediately: chest pain, severe headache, faintness, shortness of breath, or a racing heartbeat that feels abnormal. Ephedra has been linked to serious safety risks, including high blood pressure, heart attack, seizure, stroke, and psychosis.† (30)
- Avoid stacking extra stimulants: skip extra caffeine pills, energy drinks, and stimulant pre-workouts on top of these.† (29)
- Do NOT use if: you’re pregnant or nursing, under 18, or sensitive to caffeine. Also avoid these if you’re managing uncontrolled blood pressure, heart conditions, significant anxiety, or medications that may interact with stimulants.† (31) (7)
Where To Buy
We stock all five Cloma Pharma options at SameDaySupplements.com. Orders ship fast from our warehouse, and we keep these in our regular rotation because customers ask for them constantly.†
Wrapping Up
I wouldn’t chase the loudest label first. I’d start with the part of cutting that needs the most help: energy, appetite, cardio push, mental drive, or just a routine you can repeat.†
Once that’s clear, your choice gets simple. Pick the formula that fits your real schedule. Take it earlier in the day, and judge it by how well it supports your whole week. Don’t judge it only by how intense the first serving feels.†
Disclaimer
†Please note the intention of the information provided is for reference only. Furthermore, we are in no way providing medical advice or instruction. Instead, the information provided in this guide/blog utilizes anecdotal information and available studies/reviews. While we aim to maintain and display accurate information, we can’t guarantee it represents the latest product formulation or information. Therefore, please visit the manufacturer’s website if you have any concerns. Also, the information above does not represent our views here at Same Day Supplements. Instead, these are the manufacturers’ and users’ views and information. Additionally, the Food and Drug Administration has not evaluated these statements. Finally, these products aim not to diagnose, treat, cure, or prevent disease or illness.









